Which medication class is commonly used for managing hypertension?

Angiotensin-converting enzyme (ACE) inhibitors are a widely used class of medications for managing hypertension due to their ability to relax blood vessels, which in turn lowers blood pressure. ACE inhibitors work by blocking the conversion of angiotensin I to angiotensin II, a substance that narrows blood vessels. By inhibiting this conversion, ACE inhibitors help to decrease blood volume and lead to vasodilation, which results in a reduction in blood pressure. Additionally, they have protective effects on the kidneys and are especially beneficial for patients with diabetes or heart failure.

The effectiveness, coupled with a favorable safety profile, makes ACE inhibitors a cornerstone in the treatment of hypertension, often recommended as first-line therapy in guideline-based approaches. Their usage also addresses underlying conditions like chronic kidney disease, supporting both blood pressure control and renal function.